The Mike Reason collection of toy cars is to cross the block at Vectis Auctions on September 16-17.
The collection, which includes a large number of Dinky Toys, is valued at £125,000 ($192,504).
The collection includes pieces from Dinky
It also features a wealth of highly sought after pieces from Corgi and Triang.
Louise Harker from Vectis told the Daily Mirror: "After deciding to move home and downsize Mike did not want his collection to be stored away, so he made the decision to sell.
"And what better way than through the auction house where approximately 75% was purchased."
Another major collection of toy cars sold for £230,000 ($339,560) at Vectis earlier this year.
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