Barbara Hepworth's Two Forms with White (Greek) will auction this month.
The £1.8m-high estimated ($2.8m) piece is among the star lots of Christie's Modern British and Irish Art Evening Sale in London on June 25.
According to Christie's, the work "combines the symbolic and abstract, the non-representational and naturalistic".
Conceived in 1963, Hepworth produced the final bronze cast six years later in 1969.
The world record for Hepworth (1903-1975) stands at £4.1m ($6.3m), set by Figure for Landscape at Christie's last year.
Henry Moore's Rocking Chair No. 2 will also provide one of the star lots. The 1950 piece has a £1.2m ($1.8m) high estimate.
Away from the sculpture, Sir Stanley Spencer's 1955 oil work Hilda and I at Burghclere is anticipated to make up to £1.8m ($2.8m), while LS Lowry's Going to Work is valued at £1m ($1.5m).
Fans of pop artist Sir Peter Blake will be interested to see his Boys with New Ties make an appearance. The consignor bought the piece directly from Blake in 1960 for £30. It is now expected to make up to £350,000 ($533,750).
Andre Zlattinger, the head of Modern British art at Christie's London, commented: "This sale, which spans over 100 years, is defined by offering masterpieces from leading collections that celebrate the harmony and revolutionary spirit of the art of the British Isles."
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